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Cancer can cause pain by compressing organs and nerves adjacent to the tumor. A headache that does not go away or get better with treatment may be a symptom of a brain tumor. Lymph Nodes Of The Face And Neck What Causes Swollen Lymph Nodes Under The Collar Bone Swollen Lymph Nodes Lymph Nodes Lymph Massage Or from skin nerve and other changes caused by a hormone imbalance or immune response. Do cancer tumors hurt . Back pain can be a symptom of cancer of the colon rectum or ovary. Metastases to other organs. Cancer surgery treatments or tests can also cause pain. Most chronic pain is caused by the illness and most acute pain is caused by treatment or diagnostic procedures. Pain in cancer may arise from a tumor compressing or infiltrating nearby body parts. The presence of pain depends mainly on the locat. When cancer grows and harms tissue nearby it can cause pain in those areas. It releases chemicals that irritate the area around the tumor. However radiotherapy s...