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Eliquis is also used in the treatment of dvt and pulmonary embolism pe where blood clots lodge in the lungs and to lower the risk of recurrent dvt and pe. Surgery bleeding risk day preoperative doac interruption schedule postoperative doac resumption schedule day 5 4 3 2 1 day 1 day 2 3 day 4 apixaban eliquis mod high x x x low x dabigatran crcl 50ml min mod high x x x low x dabigatran crcl 50ml min mod high x x x x x low x rivaroxaban. About Dvt Pe Rx Eliquis Apixaban Safety Info Vein Thrombosis Nsaids Thrombosis High risk of bleeding 1 major surgery spinal puncture or placement of spinal epidural catheter and other situations in which complete hemostasis is required. Eliquis and surgery . Major surgery spinal anesthesia. Eliquis is indicated for the treatment of dvt. Prophylaxis of deep vein thrombosis following hip or knee replacement surgery. Time of last dose of apixaban before procedure peri procedural bridging is generally not required standard risk of bleeding. The...