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Showing posts with the label alk mutation lung cancer

Alk Cancer

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Alk positive cancer is a type of cancer with no known cause and no known cure once it has spread to other parts of the body. Younger patients usually 55 and under who have never smoked are most likely to be diagnosed as being alk. Pin On Body Alk positive cancer occurs in humans mostly as lung cancer but it can also originate in many other parts of the body including brain and breast. Alk cancer . Anaplastic lymphoma kinase alk was originally discovered in 1994 in anaplastic large cell lymphoma alcl cells. Alcl is caused by a 2 5 p23 q35 chromosomal translocation that generates the fusion protein npm alk in which the kinase domain of alk is fused to the amino terminal part of the nucleophosmin npm protein. It is thought to occur in about 100 000 people worldwide every year. When an elevated alp level is first detected via routine blood testing it usually prompts a more thorough investigation to determine potential causes. It is not thought to be a disease that is inherited...