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Take xarelto exactly as prescribed by your doctor. If you miss a dose of xarelto take it as soon as you remember on the same day. Xarelto Lawsuit Update Xarelto Side Effects This Or That Questions If anticoagulation must be discontinued to reduce the risk of bleeding associated with any surgery or procedure xarelto should be stopped at least 24 hours before the procedure. Xarelto and surgery . If oral medication cannot be taken during or after surgical procedures consider a parenteral anticoagulant. They can be stopped 2 3 days before major surgery and held one day before minor surgery. Most people who have hip replacement surgery will take xarelto 10 mg once a day for 35 days following surgery. How long should you stop taking xarelto before a colonoscopy. Take your next dose at your regularly scheduled time. How should i take xarelto. Hip or knee replacement surgery. If you take xarelto 1 time a day. Note that the half life of xarelto is 5 to 9 hours in healthy s...